VISQUE® InVivo Elite | Bio Imaging Solution | Vieworks

VISQUE®InVivo Elite

VISQUE® InVivo Elite is a preclinical in vivo fluorescent & bioluminescent imaging and analysis system.


High-Quality Camera

Thermo-electric Peltier cooling technology
Up to 24 frames per second in real time
Fluorescence and Bioluminescence imaging from visible to NIR

Easy to Control Full HD Lens with Software

Zoom with 9 steps
1x to 6x
Iris with 10 steps
f/1.8 to Close
Focus with 21 steps
0 ㎝ to 10 ㎝ (Height from the stage)
FOV (Field of View)
5 ㎝ x 4 ㎝ (6x) to 28 ㎝ x 21 ㎝ (1x)

Imaging of 5 mice at the same thime at 1.5x zoom(FOV:21cm x 16cm)

Automated Emission Filter Wheel

Hard-coating emission filters
Block to a level of OD 7
User-definable filter wheel
Accommodates up to 9 emission filters

The previous version of the filter wheel

Special Design & Tools for Real-Time Imaging

Real-time monitoring of the mouse in the dark room
Sliding stage with a teeth holder (optional)
Fixes a mouse easily and fast
Foot switch
Begins image acquisitions ASAP
Double-layer door
An inner door with an open part allows fast imaging

Representative Detectable Dyes
Representative Detectable Dyes
Excitation / Emission Fluorescent Dyes
Ex: 390 - 490 ㎚
Em:500 - 550 ㎚
GFP / EGFP / Alexa488 / FITC /
QD 525
Ex:530 - 570 ㎚
Em: 575 - 640 ㎚
RFP / DsRed / PE / Alexa 568 / TRITC / QD 585 / QD 605 / QD 625
Ex:620 - 650 ㎚
Em:690 - 740 ㎚
Ex:630 - 680 ㎚
Em:690 - 740 ㎚
Cy5.5 / PKE680 / Alexa 680 /
Alexa 700 / QD 705
Ex: 740 - 790 ㎚
Em:810 - 860 ㎚
ICG / QD800
* User defined combinations of excitations and emissions are available.
These enables you to detect other fluorescent dyes that are not listed in the table above.
Technical Specifications
Technical Specifications
  VISQUE® InVivo Elite Note
Camera Sensor 4/3" CCD  
Device Operating Temperature 10 - 28℃  
Cooling To -10℃ Delta T = -20℃
Resolution (H x V) 1,600 x 1,200  
Minimum Image Pixel Resolution 33 ㎛ (at 6x)  
Frame rate Up to 24 frames/second  
FOV (H x V) 280 x 210 mm ~ 50 x 40 mm 10 steps, 6x motorized zooming lens
Maximum Exposure time 50 mins.  
Iris / focus Motorized Max. f/1.8
Filter Selection Automated  
Excitation Light LED light Blue, Green, Red, Far-rad, NIR, White
Emission Filters Max. 5 Filters Capacity Included 4 Filters
Filter Slots 6 positions  
Anestdesia Ventilator Adaptor Yes  
Dimension / Weight 56 x 56 x 90 cm, > 100 kg  
Applications Fluorescence, Bioluminescence,
Real-time imaging
Preview capture
Specialized Functions    
Kinetics analysis Double (inner & outer) doors and
Y axis sliding stage system
Treatment, positioning and
imaging simultaneously
Stage Types 3-type stages
(5-mice / 1-mouse / 1-rat)
One stage is included in the device system
Heated stage Yes  (Off / 25℃ / 36℃)  
S/W 2 copies included Kinetics and Radiance analysis
LCD touch screen 7 inch LCD  
* Specifications are subject to change without prior notice.
* This system is only for research.

Citation Papers

Citation Papers
Title Publication (SCI) Link
A nanoscale photothermal agent based on a metal-organic coordination polymer as a drug-loading framework for effective combination therapy Acta Biomater. 2019 Aug;94:435-446 link
Blood flow characteristics of diabetic patients with complications detected by optical measurement BioMedical Engineering OnLine. 2018 17: 25 link
Age-related changes in pial arterial structure and blood flow in mice Neurobiol Aging. 2016 Jan;37:161-170 link
Exendin-4 protects hindlimb ischemic injury by inducing angiogenesis Biochem Biophys Res Commun. 2015 Oct 2;465(4):758-63. link
Use of indocyanine green for optical analysis of cortical infarcts in
photothrombotic ischemic brains
J Neurosci Methods. 2015 Jun 15;248:46-50 link
Optical measurement of mouse strain differences in cerebral
blood flow using indocyanine green
J Cereb Blood Flow Metab. 2015 Jun;35(6):912-6 link
Noninvasive Optical Measurement of Cerebral Blood
Flow in Mice Using Molecular Dynamics Analysis of
Indocyanine Green
PLoS One. 2012;7(10):e48383. link
Efficient differentiation of human pluripotent stem cells into
functional CD34 + progenitor cells by combined modulation of the
MEK/ERK and BMP4 signaling pathways
Blood. 2010 Dec 16;116(25):5762-72  link
Unsorted human adipose tissue-derived stem cells promote
angiogenesis and myogenesis in murine ischemic hindlimb model
Microvasc Res. 2010 Dec;80(3):310-6. link
Quantitative Analysis of Peripheral Tissue Perfusion
Using Spatiotemporal Molecular Dynamics
PLoS One. 2009;4(1):e4275. link


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User manual
DOWNLOADVISQUE InVivo Elite User Manual_V1.5.EN.pdf